Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.81 |
| ▸ | HTR2A | P28223 | 17/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093740 | 1.00 | HTR2C (0.81) | HTR2CHTR2AHTR2BCYP1A2CYP3A4 | |
| Fumaric Acid SCHEMBL7088510 | 0.89 | HTR2C (0.64) | HTR2CHTR2AHTR2B | |
| Fumaric Acid SCHEMBL7088508 | 0.89 | HTR2C (0.64) | HTR2CHTR2AHTR2B | |
| SCHEMBL7983641 | 0.88 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL7983649 | 0.88 | HTR2C (0.63) | HTR2CHTR2AHTR2B | |
| SCHEMBL12386902 | 0.84 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL8596900 | 0.81 | HTR2C (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL8596238 | 0.81 | HTR2C (0.66) | HTR2CHTR2AHTR2B | |
| SCHEMBL14527161 | 0.81 | HTR2C (0.57) | HTR2CHTR2AHTR2BCYP1A2CYP3A4 | |
| SCHEMBL9230485 | 0.80 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |