Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4555592 | 0.84 | ALOX5 (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8765867 | 0.84 | CYP1A2 (0.47) | TAAR1MEN1ALDH1A1POLBMAPT | |
| SCHEMBL9544466 | 0.84 | CYP1A2 (0.47) | TAAR1MEN1ALDH1A1POLBMAPT | |
| SCHEMBL8765558 | 0.80 | TAAR1 (0.43) | TAAR1MEN1ALDH1A1POLBMAPT | |
| SCHEMBL9356423 | 0.79 | CPA1 (0.44) | TAAR1POLB | |
| SCHEMBL14402404 | 0.75 | TAAR1 (0.58) | TAAR1CMA1TAS1R3TAS1R1IDO1 | |
| SCHEMBL14402407 | 0.75 | TAAR1 (0.58) | TAAR1TAS1R3TAS1R1IDO1AGXT | |
| SCHEMBL13849891 | 0.75 | TAAR1 (0.58) | TAAR1TAS1R3TAS1R1IDO1AGXT | |
| SCHEMBL13349249 | 0.75 | TAAR1 (0.68) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL15121492 | 0.75 | TAAR1 (0.58) | TAAR1CMA1TAS1R3TAS1R1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627648-A1 | 17aHYDROXYLASE/C17,20-LYASE INHIBITORS | Novartis AG (CH) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |