Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985910 | 0.87 | PTGS2 (0.57) | MAPK14 | |
| SCHEMBL7985400 | 0.85 | PTGS1 (0.55) | — | |
| SCHEMBL9382851 | 0.83 | ABL1 (0.47) | KMT2AABL1ABCB1BCRAXL | |
| SCHEMBL12801025 | 0.78 | BRD4 (0.50) | — | |
| SCHEMBL28260523 | 0.76 | GCGR (0.64) | GCGRMAPK14KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11263859 | 0.76 | GCGR (0.47) | GCGRMAPK14KMT2AABL1ABCB1 | |
| SCHEMBL6195404 | 0.76 | SMN1; SMN2 (0.47) | GCGRMAPK14SMN1; SMN2 | |
| SCHEMBL15450946 | 0.75 | ABL1 (0.47) | KMT2AABL1ABCB1BCRAXL | |
| SCHEMBL11311376 | 0.75 | PARP1 (0.45) | KMT2AABL1ABCB1BCRGSK3B | |
| SCHEMBL11258346 | 0.75 | SMN1; SMN2 (0.54) | GCGRMAPK14KMT2AMEN1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| US-4477463-A | Antiinflammatory and/or analgesic 1-alkyl-4,5-diaryl-2-fluoroalkyl-1H-pyrroles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
| US-4318917-A | PREPARED FROM A PYRROLE COMPOUND AND A 1-3-DITHIETANE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |