Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003874 | 0.82 | KDM4E (0.40) | PDE10AMAPTMAPK1L3MBTL1KCNN4 | |
| SCHEMBL27558061 | 0.79 | TRPA1 (0.41) | PDE10AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL7404589 | 0.79 | HTR1B (0.51) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2354192 | 0.79 | PDCD1 (0.47) | PDCD1CD274MAPTMAPK1TDP1 | |
| SCHEMBL4848836 | 0.77 | TSHR (0.37) | PDCD1CD274S1PR1ALDH1A1LMNA | |
| SCHEMBL5203294 | 0.76 | TSHR (0.45) | PDE10AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL16955136 | 0.76 | PDCD1 (0.44) | PDCD1CD274MAPTMAPK1TDP1 | |
| SCHEMBL8760084 | 0.76 | MRGPRX4 (0.44) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL3903483 | 0.76 | PDCD1 (0.44) | PDCD1CD274MAPTMAPK1TDP1 | |
| SCHEMBL13696492 | 0.76 | KCNN4 (0.44) | PDE10AMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |