Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7981811 | 0.99 | KCNH2 (0.40) | KCNH2MAOAMAOBFAAHSLC6A2 | |
| SCHEMBL7989283 | 0.96 | CHRM4 (0.37) | KCNH2MAOAMAOBFAAHSLC6A2 | |
| Hydrochloric Acid SCHEMBL7983317 | 0.95 | CHRM4 (0.36) | KCNH2MAOAMAOBFAAHSLC6A2 | |
| SCHEMBL7986225 | 0.95 | MAOA (0.42) | KCNH2MAOAMAOBCHRM4 | |
| Hydrochloric Acid SCHEMBL7973072 | 0.95 | KCNH2 (0.41) | KCNH2MAOAMAOBCHRM4 | |
| SCHEMBL7982308 | 0.92 | CHRM4 (0.41) | MAOAMAOBCHRM4 | |
| Hydrochloric Acid SCHEMBL7972053 | 0.92 | CHRM4 (0.40) | KCNH2MAOAMAOBCHRM4 | |
| SCHEMBL7971862 | 0.91 | TP53 (0.40) | KCNH2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7982031 | 0.90 | TP53 (0.39) | KCNH2SLC6A4 | |
| SCHEMBL7990681 | 0.89 | CHRM4 (0.43) | MAOAMAOBSLC6A2SLC6A4CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |