Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983744 | 0.88 | LMNA (0.43) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7997664 | 0.77 | GFER (0.36) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7995873 | 0.77 | LMNA (0.45) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7983888 | 0.76 | LMNA (0.43) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7996728 | 0.74 | LMNA (0.42) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7983644 | 0.74 | LMNA (0.42) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7997919 | 0.74 | SMN1; SMN2 (0.46) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7997799 | 0.73 | LMNA (0.41) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7994286 | 0.73 | LMNA (0.41) | LMNATSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7994274 | 0.72 | LMNA (0.46) | LMNATSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |