Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842587 | 1.00 | CTSS (0.53) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL6842589 | 1.00 | CTSS (0.53) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL5738490 | 0.88 | CTSS (0.51) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL20516430 | 0.87 | ATM (0.52) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL20516427 | 0.87 | ATM (0.52) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL16453567 | 0.86 | CTSS (0.53) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL10416562 | 0.86 | CTSS (0.53) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL20516388 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL20516385 | 0.86 | CTSS (0.68) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL16087907 | 0.85 | ATM (0.53) | CTSSCTSKCTSLCTSBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262040-B1 | Indazole derivatives and their use as inhibitors of phosphodiesterase (PDE) type IV and the production of tumor necrosis factor (TNF) | PFIZER INC | 2001-07-17 | — | — | US | disclosed |