Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981751 | 0.96 | SIGMAR1 (0.51) | SIGMAR1PNMT | |
| SCHEMBL7981914 | 0.94 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL7984338 | 0.89 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL7970219 | 0.87 | MEN1 (0.46) | PNMT | |
| SCHEMBL7988064 | 0.84 | SIGMAR1 (0.47) | SIGMAR1PNMT | |
| SCHEMBL7981495 | 0.82 | MEN1 (0.46) | PNMT | |
| SCHEMBL7980579 | 0.80 | SIGMAR1 (0.47) | SIGMAR1PNMT | |
| SCHEMBL6780229 | 0.78 | GRIA1 (0.51) | — | |
| SCHEMBL7980695 | 0.77 | GAA (0.47) | SIGMAR1 | |
| SCHEMBL9091690 | 0.76 | CYP19A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197771-B1 | NERVOUS SYSTEM DISORDERS; ANTIISCHEMIC AGENTS; ALZHEIMER'SDISEASE; PARKINSON'S DISEASE; HUNTINGTON'S DISEASE | WARNER-LAMBERT COMPANY | 2001-03-06 | — | — | US | claimed |
| WO-1996028445-A1 | NOVEL GLUTAMATE (AMPA/KAINATE) RECEPTOR ANTAGONISTS: N-SUBSTITUTED FUSED AZACYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-09-19 | — | — | WO | claimed |
| US-6197771-B1 | NERVOUS SYSTEM DISORDERS; ANTIISCHEMIC AGENTS; ALZHEIMER'SDISEASE; PARKINSON'S DISEASE; HUNTINGTON'S DISEASE | WARNER-LAMBERT COMPANY | 2001-03-06 | — | — | US | disclosed |
| US-6057313-A | TREATING CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1996028445-A1 | NOVEL GLUTAMATE (AMPA/KAINATE) RECEPTOR ANTAGONISTS: N-SUBSTITUTED FUSED AZACYCLOALKYLQUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1996-09-19 | — | — | WO | disclosed |