Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994205 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL7983909 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL7984266 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HSD17B10 | |
| SCHEMBL7983724 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL7983835 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL7983841 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL7994647 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL8001463 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT | |
| SCHEMBL7984881 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HTTLMNAMAPT | |
| SCHEMBL7995844 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP11B1CYP11B2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |