Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984881 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL8001766 | 0.91 | NPC1 (0.49) | SMN1; SMN2HTTMAPTLMNAALDH1A1 | |
| SCHEMBL7984548 | 0.90 | CDYL2 (0.45) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL8002185 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL7983724 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL7983861 | 0.81 | NPSR1 (0.51) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL7983909 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL7995844 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTMAPTLMNAKDM4E | |
| SCHEMBL7983841 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAPTLMNAALDH1A1 | |
| SCHEMBL7984271 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |