Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | PRNP | P04156 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13963145 | 0.82 | HSD11B1 (0.62) | HSD11B1RXFP1PRNPKDM4EL3MBTL1 | |
| SCHEMBL4834908 | 0.82 | HSD11B1 (0.62) | HSD11B1RXFP1PRNPKDM4EPTGS2 | |
| SCHEMBL4775261 | 0.81 | HSD11B1 (0.61) | HSD11B1RXFP1PRNPKDM4EHPGD | |
| SCHEMBL14380707 | 0.81 | HSD11B1 (0.61) | HSD11B1RXFP1PRNPKDM4EHPGD | |
| SCHEMBL7984156 | 0.81 | HSD11B1 (0.61) | HSD11B1RXFP1PRNPKDM4EL3MBTL1 | |
| SCHEMBL2099000 | 0.81 | HSD11B1 (0.61) | HSD11B1RXFP1PRNPKDM4EPTGS2 | |
| SCHEMBL584871 | 0.80 | RXFP1 (0.71) | HSD11B1RXFP1PRNPKDM4EHPGD | |
| SCHEMBL29939764 | 0.80 | RXFP1 (0.71) | HSD11B1RXFP1PRNPKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL4775352 | 0.79 | HSD11B1 (0.59) | HSD11B1RXFP1PRNPKDM4EHPGD | |
| SCHEMBL718477 | 0.78 | HSD11B1 (0.58) | HSD11B1RXFP1PRNPKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |