Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30693720 | 0.85 | PRNP (0.49) | HSD11B1PRNPRXFP1KDM4EKMT2A | |
| SCHEMBL586189 | 0.85 | PRNP (0.49) | HSD11B1PRNPRXFP1KDM4EKMT2A | |
| SCHEMBL12359739 | 0.82 | PRNP (0.45) | HSD11B1PRNPRXFP1ALDH1A1LMNA | |
| SCHEMBL4775819 | 0.81 | TAS1R3 (0.44) | HSD11B1PRNPRXFP1KDM4EGLA | |
| SCHEMBL5739446 | 0.81 | RXFP1 (0.44) | HSD11B1PRNPRXFP1ALDH1A1TAS1R3 | |
| SCHEMBL13911292 | 0.79 | TAS1R3 (0.43) | HSD11B1PRNPRXFP1GLAKMT2A | |
| SCHEMBL11199425 | 0.78 | TAS1R3 (0.45) | HSD11B1PRNPRXFP1KDM4EGLA | |
| SCHEMBL13900908 | 0.78 | TAS1R3 (0.43) | HSD11B1PRNPRXFP1ALDH1A1TAS1R3 | |
| SCHEMBL2324454 | 0.78 | TAS1R3 (0.45) | HSD11B1PRNPRXFP1ALDH1A1TAS1R3 | |
| SCHEMBL12374285 | 0.77 | TAS1R3 (0.42) | HSD11B1PRNPRXFP1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |