Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988135 | 0.81 | BRD4 (0.53) | HSD17B10SMN1; SMN2PARP1BRD4CREBBP | |
| SCHEMBL7711230 | 0.80 | PARP1 (0.37) | CHRM1PARP1BRD4CREBBPAHR | |
| SCHEMBL7000474 | 0.80 | PARP1 (0.37) | SMN1; SMN2PARP1BRD4CREBBPPDE3B | |
| SCHEMBL5670852 | 0.80 | PARP1 (0.60) | HSD17B10TP53POLBSMN1; SMN2PARP1 | |
| SCHEMBL7981172 | 0.78 | PARP1 (0.35) | HSD17B10PARP1BRD4CREBBPPDE3B | |
| SCHEMBL6998842 | 0.76 | ACE2 (0.40) | HSD17B10CHRM1PARP1BRD4CREBBP | |
| SCHEMBL6995122 | 0.76 | ABCB1 (0.38) | PGRPARP1BRD4CREBBPPDE3B | |
| SCHEMBL7000985 | 0.76 | KDM4E (0.54) | CHRM1NR3C1PGRPARP1PDE3B | |
| SCHEMBL6996429 | 0.74 | ALDH1A1 (0.40) | HSD17B10CHRM1NR3C1PGRAR | |
| SCHEMBL7710980 | 0.74 | ALDH1A1 (0.52) | HSD17B10SMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| US-6008218-A | FUNGICIDES; CHEMICAL INTERMEDIATES | UBE INDUSTRIES, LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0913395-A1 | N-PHENYLCARBAMATE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL OR HORTICULTURAL BACTERICIDES | UBE INDUSTRIES, LTD. (JP) | 1999-05-06 | — | — | EP | disclosed |