Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887739 | 0.87 | PDE7A (0.53) | ALDH1A1CACNA2D1PDE7A | |
| SCHEMBL8423977 | 0.85 | TDP1 (0.51) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8424795 | 0.85 | TDP1 (0.51) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9027995 | 0.82 | TDP1 (0.73) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL12963478 | 0.80 | MEN1 (0.52) | ALDH1A1SMN1; SMN2CACNA2D1POLBTSHR | |
| SCHEMBL8422380 | 0.80 | TDP1 (0.49) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8423016 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8424708 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL31241091 | 0.79 | CACNA2D1 (0.47) | ALDH1A1LMNACACNA2D1POLB | |
| SCHEMBL31241088 | 0.79 | CACNA2D1 (0.48) | ALDH1A1SMN1; SMN2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255311-B1 | FOR PLANTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-07-03 | — | — | US | claimed |
| US-6255311-B1 | FOR PLANTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-07-03 | — | — | US | disclosed |
| US-5945423-A | FOR AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5747497-A | Fungicidal fused bicyclic pyrimidinones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| WO-1994026722-A1 | FUNGICIDAL FUSED BICYCLIC PYRIMIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |