Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423016 | 0.94 | TDP1 (0.46) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8422380 | 0.81 | TDP1 (0.49) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8423977 | 0.79 | TDP1 (0.51) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8424795 | 0.79 | TDP1 (0.51) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8651483 | 0.79 | TDP1 (0.43) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL9027995 | 0.76 | TDP1 (0.73) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL8426424 | 0.73 | TDP1 (0.43) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL5712377 | 0.71 | ALDH1A1 (0.52) | TDP1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8424272 | 0.69 | MAPT (0.45) | TDP1ALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL7100456 | 0.67 | DHFR (0.43) | ALDH1A1LMNAKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946095-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026664-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |