Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | LPO | P22079 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | CD74 | P04233 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984135 | 0.92 | GAA (0.49) | GAATP53RXFP1YTHDC1LPO | |
| SCHEMBL7986363 | 0.88 | GAA (0.48) | GAATP53RXFP1YTHDC1LPO | |
| SCHEMBL7985274 | 0.88 | GAA (0.48) | GAATP53RXFP1YTHDC1LPO | |
| Hydrochloric Acid SCHEMBL7974230 | 0.87 | GAA (0.47) | GAATP53RXFP1YTHDC1LPO | |
| SCHEMBL7974260 | 0.85 | CYP11B1 (0.47) | GAATP53ADORA2AADORA1LMNA | |
| SCHEMBL7984208 | 0.84 | MAPT (0.39) | GAARXFP1LMNAMAPT | |
| SCHEMBL7984754 | 0.84 | SMN1; SMN2 (0.47) | GAAYTHDC1ADORA2AADORA1 | |
| SCHEMBL7985850 | 0.83 | GAA (0.49) | GAATP53RXFP1YTHDC1LPO | |
| SCHEMBL7975252 | 0.83 | HPGD (0.45) | GAARXFP1YTHDC1MEN1KMT2A | |
| SCHEMBL7987469 | 0.83 | TLR7 (0.44) | LMNAMEN1KMT2AQPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |