Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994205 | 0.90 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2LMNAHTTRECQL | |
| SCHEMBL8002185 | 0.86 | SMN1; SMN2 (0.52) | MAPTCCNT1CDK9SMN1; SMN2LMNA | |
| SCHEMBL7984881 | 0.84 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8001766 | 0.83 | NPC1 (0.49) | MAPTSMN1; SMN2LMNAHTTRECQL | |
| SCHEMBL7983724 | 0.79 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL7995844 | 0.77 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2LMNAGAAHTT | |
| SCHEMBL7983861 | 0.76 | NPSR1 (0.51) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL7983909 | 0.76 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2LMNAGAAHTT | |
| SCHEMBL7983841 | 0.74 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2LMNAGAAHTT | |
| Hydrochloric Acid SCHEMBL8001463 | 0.74 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |