Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 9/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988006 | 0.99 | CNOT7 (0.43) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7984709 | 0.93 | CNOT7 (0.42) | CNOT7TSHRKMT2AALDH1A1ADORA2A | |
| Hydrochloric Acid SCHEMBL7984350 | 0.92 | CNOT7 (0.41) | CNOT7KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7987235 | 0.87 | TSHR (0.46) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7974254 | 0.87 | TSHR (0.46) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7984365 | 0.86 | HPGD (0.45) | CNOT7TSHRKMT2AALDH1A1TLR7 | |
| Hydrochloric Acid SCHEMBL7992066 | 0.85 | HPGD (0.44) | CNOT7TSHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL7988857 | 0.84 | CNOT7 (0.43) | CNOT7TSHRKDM4ELMNAPOLB | |
| SCHEMBL7985082 | 0.80 | HTT (0.46) | CNOT7TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL7974534 | 0.80 | CNOT7 (0.45) | CNOT7TSHRKMT2AALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |