Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987235 | 0.93 | TSHR (0.46) | TSHRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7974534 | 0.93 | CNOT7 (0.45) | TSHRCNOT7ALDH1A1KMT2AADORA2A | |
| SCHEMBL7984944 | 0.87 | CNOT7 (0.44) | TSHRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7988857 | 0.87 | CNOT7 (0.43) | TSHRKDM4ELMNAPOLBMAPK1 | |
| Hydrochloric Acid SCHEMBL7988006 | 0.86 | CNOT7 (0.43) | TSHRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7985082 | 0.85 | HTT (0.46) | TSHRLMNACNOT7ALDH1A1KMT2A | |
| SCHEMBL7975252 | 0.85 | HPGD (0.45) | TSHRPOLBCNOT7ALDH1A1MEN1 | |
| SCHEMBL7985536 | 0.84 | SMN1; SMN2 (0.42) | TSHRKDM4ELMNACNOT7ALDH1A1 | |
| SCHEMBL7984242 | 0.81 | CNOT7 (0.45) | TSHRKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL7985772 | 0.81 | L3MBTL1 (0.45) | TSHRLMNACNOT7ALDH1A1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |