Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985098 | 0.86 | HSD11B1 (0.49) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL7968044 | 0.84 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL7995018 | 0.84 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL12671020 | 0.84 | HSD11B1 (0.46) | HSD11B1ALDH1A1KDM4EHPGDOXTR | |
| SCHEMBL7988162 | 0.83 | HSD11B1 (0.54) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL1417729 | 0.78 | HSD11B1 (0.59) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL1417458 | 0.78 | HSD11B1 (0.59) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL7984543 | 0.76 | HSD11B1 (0.54) | HSD11B1 | |
| SCHEMBL2983487 | 0.75 | HSD11B1 (0.67) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL18905854 | 0.74 | HSD11B1 (0.71) | HSD11B1ALDH1A1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |