Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119554 | 0.89 | BPTF (0.31) | — | |
| SCHEMBL7984107 | 0.80 | ALDH1A1 (0.32) | CRHR1 | |
| SCHEMBL2646178 | 0.74 | CYP1A2 (0.48) | TDP1MEN1GFERKMT2A | |
| SCHEMBL30893809 | 0.74 | CYP1A2 (0.48) | TDP1MEN1GFERKMT2A | |
| SCHEMBL195203 | 0.71 | BPTF (0.51) | MEN1KMT2A | |
| SCHEMBL2647859 | 0.71 | MAPT (0.46) | TDP1KMT2A | |
| SCHEMBL30378500 | 0.71 | MAPT (0.46) | TDP1KMT2A | |
| SCHEMBL30282824 | 0.71 | BPTF (0.51) | MEN1KMT2A | |
| SCHEMBL1976538 | 0.70 | CYP1A2 (0.58) | MEN1KMT2A | |
| SCHEMBL24961981 | 0.69 | CNR2 (0.37) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319924-B1 | FOR THERAPY OF DELETERIOUS MENTAL STATES | MERCK SHARP & DOHME LTD. (GB) | 2001-11-20 | — | — | US | disclosed |
| EP-1056747-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999037649-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1999-07-29 | — | — | WO | disclosed |