Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984452 | 0.79 | PARP1 (0.45) | PARP1BRD4CREBBPTP53MAPT | |
| SCHEMBL1451025 | 0.77 | PARP1 (1.00) | PARP1BRD4CREBBPBRPF1TP53 | |
| SCHEMBL26472774 | 0.76 | PARP1 (0.57) | PARP1TP53MAPTTHRBALDH1A1 | |
| SCHEMBL17517851 | 0.74 | GSK3B (0.44) | PARP1BRD4KMT2AMEN1 | |
| SCHEMBL19429612 | 0.73 | PARP1 (0.62) | PARP1BRD4CREBBPTP53MAPT | |
| SCHEMBL29999040 | 0.73 | PARP1 (0.62) | PARP1BRD4CREBBPTP53MAPT | |
| SCHEMBL7155529 | 0.73 | PARP1 (0.62) | PARP1BRD4CREBBPBRPF1TP53 | |
| SCHEMBL7121791 | 0.73 | PARP1 (0.62) | PARP1BRD4CREBBPBRPF1TP53 | |
| SCHEMBL13273256 | 0.73 | PARP1 (0.62) | PARP1BRD4CREBBPBRPF1TP53 | |
| SCHEMBL17676993 | 0.73 | CREBBP (0.58) | PARP1BRD4CREBBPBRPF1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |