Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.42 |
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985301 | 0.99 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 | |
| SCHEMBL7985358 | 0.82 | CNOT7 (0.50) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 | |
| SCHEMBL7974098 | 0.81 | KMT2A (0.55) | KMT2ASMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL7985306 | 0.81 | CNOT7 (0.51) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 | |
| SCHEMBL7974022 | 0.77 | SMN1; SMN2 (0.62) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 | |
| SCHEMBL1713573 | 0.77 | PNP (0.64) | KMT2ASMN1; SMN2ALDH1A1HPGDPNP | |
| Hydrochloric Acid SCHEMBL7773119 | 0.76 | PNP (0.63) | KMT2ASMN1; SMN2ALDH1A1HPGDPNP | |
| Hydrochloric Acid SCHEMBL5718893 | 0.76 | PNP (0.63) | KMT2ASMN1; SMN2ALDH1A1HPGDPNP | |
| SCHEMBL7975265 | 0.76 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 | |
| SCHEMBL7975251 | 0.75 | SMN1; SMN2 (0.60) | KMT2ASMN1; SMN2ALDH1A1HPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |