Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 2/20 | 0.47 |
| ▸ | PARN | O95453 | 1/20 | 0.47 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974445 | 0.93 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7991402 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7984453 | 0.93 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7975129 | 0.93 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7974505 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7984716 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7988556 | 0.92 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| Hydrochloric Acid SCHEMBL7985511 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7986518 | 0.92 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 | |
| SCHEMBL7988662 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |
| EP-0538332-A1 | POLYCYCLIC GUANINE DERIVATIVES. | SCHERING CORP (US) | 1993-04-28 | — | — | EP | disclosed |