SCHEMBL7985356

SCHEMBL7985356

Cn1c(-c2ccccc2C(F)(F)F)nnc1C(C)(C)Oc1ccc(N)cc1C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 17/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974781 0.92 HSD11B1 (0.52) HSD11B1
SCHEMBL7988223 0.91 HSD11B1 (0.54) HSD11B1
SCHEMBL7988848 0.91 HSD11B1 (0.54) HSD11B1
SCHEMBL7981036 0.87 HSD11B1 (0.67) HSD11B1
SCHEMBL7981671 0.86 HSD11B1 (0.52) HSD11B1
SCHEMBL7980361 0.85 HSD11B1 (0.57) HSD11B1
SCHEMBL7968485 0.85 HSD11B1 (0.47) HSD11B1
SCHEMBL7982023 0.85 HSD11B1 (0.44) HSD11B1
SCHEMBL7984098 0.84 HSD11B1 (0.42) HSD11B1
SCHEMBL7985123 0.84 HSD11B1 (0.50) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010001946-A1 TRIAZOLE DERIVATIVE OR SALT THEREOF アステラス製薬株式会社 (JP) 2010-01-07 WO disclosed