Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794781 | 0.81 | MAPT (0.46) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL6927981 | 0.79 | MAPT (0.44) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL16198983 | 0.76 | MAPT (0.48) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL592859 | 0.76 | MAPT (0.48) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL2932077 | 0.76 | MAPT (0.48) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL6929222 | 0.74 | MAPT (0.42) | MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL8775369 | 0.73 | CES2 (0.54) | MAPTLMNAL3MBTL1 | |
| SCHEMBL8775172 | 0.73 | CES2 (0.54) | MAPTLMNAL3MBTL1 | |
| SCHEMBL8775076 | 0.73 | CES2 (0.54) | MAPTLMNAL3MBTL1 | |
| SCHEMBL6934073 | 0.73 | CES2 (0.54) | MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0938482-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | Oxis International, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998007714-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | OXIS INTERNATIONAL, INC. (US) | 1998-02-26 | — | — | WO | disclosed |