SCHEMBL7985487

SCHEMBL7985487

O=C1CCC2CC=NC=C2N1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.33
DDB1 Q16531 18/20 0.33
IKZF3 Q9UKT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68773 0.69 CRBN (0.33) CRBNDDB1IKZF3
SCHEMBL33371399 0.69 CRBN (0.33) CRBNDDB1IKZF3
SCHEMBL12473611 0.67 CRBN (0.32) CRBNDDB1
SCHEMBL2974249 0.67 CRBN (0.32) CRBNDDB1IKZF3
SCHEMBL7099066 0.64 CRBN (0.33) CRBNDDB1IKZF3
SCHEMBL4432323 0.62
SCHEMBL9731788 0.62 MAPT (0.34) CRBNDDB1
SCHEMBL350287 0.62
SCHEMBL15703044 0.61 DDB1 (0.36) CRBNDDB1
SCHEMBL6232358 0.61 CRBN (0.33) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346922-A1 COMPOUNDS FOR IMPROVEMENT OF VIRAL PRODUCTION TENAYA THERAPEUTICS INC (US) 2025-11-13 US disclosed
US-12201617-B2 HDAC6 inhibitors for treatment of metabolic disease and HFpEF TENAYA THERAPEUTICS, INC. (US) 2025-01-21 US disclosed
US-20240252502-A1 HDAC6 INHIBITORS FOR TREATMENT OF METABOLIC DISEASE AND HFPEF TENAYA THERAPEUTICS, INC. 2024-08-01 US disclosed
US-20230381148-A1 HDAC6 INHIBITORS FOR TREATMENT OF METABOLIC DISEASE AND HFPEF TENAYA THERAPEUTICS, INC. 2023-11-30 US disclosed
US-6265406-B1 VIRICIDES DUPONT PHARMACEUTICALS COMPANY 2001-07-24 US disclosed
US-6090821-A ENZYME INHIBITORS; VIRICIDES E. I. DUPONT DE NEMOURS AND COMPANY (US) 2000-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381148-A1 HDAC6 INHIBITORS FOR TREATMENT OF METABOLIC DISEASE AND HFPEF HDAC6, HDAC1, HDAC2 CRBN 4370/4885DDB1 4521/4885IKZF3 2945/4885
US-20240252502-A1 HDAC6 INHIBITORS FOR TREATMENT OF METABOLIC DISEASE AND HFPEF HDAC6, HDAC1, HDAC2 CRBN 4370/4885DDB1 4521/4885IKZF3 2945/4885
US-12201617-B2 HDAC6 inhibitors for treatment of metabolic disease and HFpEF HDAC6, HDAC1, HDAC2 CRBN 4370/4885DDB1 4521/4885IKZF3 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.