Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985775 | 0.94 | CNOT7 (0.58) | CNOT7LMNAL3MBTL1POLBKMT2A | |
| SCHEMBL7974538 | 0.82 | CNOT7 (0.57) | CNOT7LMNATSHRHTTPOLB | |
| SCHEMBL7985534 | 0.82 | L3MBTL1 (0.44) | CNOT7LMNASMN1; SMN2ALOX15TSHR | |
| SCHEMBL7975254 | 0.80 | CNOT7 (0.55) | CNOT7SMN1; SMN2POLBKMT2A | |
| SCHEMBL7985450 | 0.78 | CNOT7 (0.48) | CNOT7LMNASMN1; SMN2ALOX15TSHR | |
| SCHEMBL7987237 | 0.77 | CNOT7 (0.57) | CNOT7LMNATSHRPOLBMAPK1 | |
| SCHEMBL7985770 | 0.76 | CNOT7 (0.50) | CNOT7LMNASMN1; SMN2ALOX15TSHR | |
| SCHEMBL7973938 | 0.76 | CNOT7 (0.48) | CNOT7SMN1; SMN2L3MBTL1TP53KMT2A | |
| SCHEMBL7984516 | 0.75 | TP53 (0.53) | LMNAMAPTTP53 | |
| SCHEMBL7985085 | 0.74 | CNOT7 (0.56) | CNOT7LMNATSHRPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |