Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989514 | 0.90 | GAA (0.46) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL11974037 | 0.86 | POLB (0.58) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL16256877 | 0.86 | LMNA (0.58) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL725320 | 0.86 | LMNA (0.58) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL7986406 | 0.85 | GAA (0.59) | POLBSMN1; SMN2GAACHRM1ATM | |
| SCHEMBL726694 | 0.84 | SMN1; SMN2 (0.56) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL3994255 | 0.84 | POLB (0.56) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL30510136 | 0.84 | SMN1; SMN2 (0.56) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL7449135 | 0.83 | POLB (0.63) | LMNAPOLBSMN1; SMN2GAACHRM1 | |
| SCHEMBL7448604 | 0.83 | LMNA (0.55) | LMNAPOLBSMN1; SMN2GAACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1328278-C | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2007-07-25 | — | — | CN | disclosed |
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| CN-1265661-A | N-acylamino acid amide compounds and intermediates for preparation thereof | UBE INDUSTRIES (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |