Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7989917 | 0.91 | F2 (0.63) | F2MEN1KMT2AESR1ESR2 | |
| SCHEMBL7985805 | 0.90 | F2 (0.66) | F2ESR1ESR2 | |
| SCHEMBL7990712 | 0.87 | F2 (0.80) | F2ESR1ESR2 | |
| SCHEMBL6596059 | 0.86 | F2 (0.78) | F2ESR1ESR2 | |
| SCHEMBL7972046 | 0.86 | F2 (0.66) | F2ESR1ESR2 | |
| SCHEMBL7987881 | 0.85 | F2 (0.67) | F2ESR1ESR2 | |
| SCHEMBL7986605 | 0.84 | ESR1 (0.55) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL7981827 | 0.84 | F2 (0.65) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL7986656 | 0.83 | F2 (0.52) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6593888 | 0.83 | F2 (0.75) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |