Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.65 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7989917 | 0.92 | F2 (0.63) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL6593888 | 0.92 | F2 (0.75) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL7971937 | 0.91 | F2 (0.79) | F2ESR1ESR2 | |
| SCHEMBL7987881 | 0.91 | F2 (0.67) | F2ESR1ESR2 | |
| SCHEMBL7985805 | 0.89 | F2 (0.66) | F2ESR1ESR2 | |
| SCHEMBL7989741 | 0.88 | F2 (0.70) | F2ESR1ESR2 | |
| SCHEMBL6596200 | 0.87 | F2 (0.80) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL7986090 | 0.84 | ITGA4 (0.60) | F2ESR1ESR2 | |
| Oxalic Acid SCHEMBL7985630 | 0.84 | F2 (0.61) | F2ESR1ESR2 | |
| SCHEMBL7775907 | 0.83 | F2 (0.74) | F2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |