Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.42 |
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975254 | 0.87 | CNOT7 (0.55) | CNOT7PARNALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL7973938 | 0.85 | CNOT7 (0.48) | CNOT7PARNDAOALDH1A1SMN1; SMN2 | |
| SCHEMBL7974262 | 0.84 | ALDH1A1 (0.45) | CNOT7PARNCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984516 | 0.84 | TP53 (0.53) | — | |
| SCHEMBL7987439 | 0.83 | CNOT7 (0.43) | CNOT7PARNCYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984758 | 0.83 | SMN1; SMN2 (0.51) | CNOT7PARNSMN1; SMN2 | |
| SCHEMBL7984210 | 0.83 | GRIN1 (0.43) | CNOT7PARNALDH1A1HPGD | |
| SCHEMBL7987785 | 0.83 | PARN (0.47) | CNOT7PARNALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL7984530 | 0.82 | HPGD (0.46) | CNOT7PARNALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7988132 | 0.82 | CNOT7 (0.44) | CNOT7PARNALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |