Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987702 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7991666 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| Hydrochloric Acid SCHEMBL7987857 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7985704 | 0.84 | CNOT7 (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2AHTT | |
| SCHEMBL7989405 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7988836 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| Hydrochloric Acid SCHEMBL7975095 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7987608 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7985634 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7985298 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1HPGDKMT2APARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |