Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.64 |
| ▸ | BCHE | P06276 | 5/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373159 | 0.94 | CHRM2 (0.67) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL9517424 | 0.94 | CHRM2 (0.70) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| Bromide SCHEMBL9649046 | 0.92 | CHRM2 (0.68) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL18114970 | 0.89 | CHRM2 (0.77) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL5099393 | 0.86 | TAAR1 (0.68) | BCHECHRM2CHRM1CHRM3MTNR1A | |
| SCHEMBL3621768 | 0.86 | SIGMAR1 (0.70) | SIGMAR1BCHEHTR2ADRD2DRD4 | |
| SCHEMBL3164467 | 0.85 | CHRM2 (0.66) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL5678830 | 0.85 | CHRM2 (0.66) | SIGMAR1CHRM2CHRM1CHRM3MTNR1A | |
| Hydrochloric Acid SCHEMBL11814390 | 0.85 | SLC2A1 (0.62) | SIGMAR1BCHECHRM2CHRM1CHRM3 | |
| SCHEMBL29194688 | 0.84 | BCHE (0.80) | BCHECHRM2CHRM1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873298-A4 | CHIRAL REDUCTIONS OF IMINES LEADING TO THE SYNTHESES OF OPTICALLY ACTIVE AMINES | NPS PHARMA INC (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0873298-A1 | CHIRAL REDUCTIONS OF IMINES LEADING TO THE SYNTHESES OF OPTICALLY ACTIVE AMINES | NPS PHARMACEUTICALS, INC. (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997011934-A1 | CHIRAL REDUCTIONS OF IMINES LEADING TO THE SYNTHESES OF OPTICALLY ACTIVE AMINES | NPS PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |