Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 16/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 16/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982795 | 0.91 | ITGB3 (0.41) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7982790 | 0.89 | ITGB3 (0.41) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7980535 | 0.88 | ITGB3 (0.43) | ITGAVITGB3ITGA2B | |
| SCHEMBL7979200 | 0.87 | ITGB3 (0.44) | ITGAVITGB3ITGA2B | |
| SCHEMBL7969254 | 0.86 | ITGB3 (0.46) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7985888 | 0.86 | ITGAV (0.52) | ITGAVITGB3ITGA2B | |
| SCHEMBL7355763 | 0.85 | ITGB3 (0.58) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7985819 | 0.84 | ITGB3 (0.61) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982887 | 0.81 | ITGAV (0.64) | ITGAVITGB3ITGA2B | |
| SCHEMBL7969234 | 0.81 | ITGAV (0.48) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |