Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983488 | 0.96 | MAPK14 (0.54) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| Dimethylamine SCHEMBL7986172 | 0.88 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7985927 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7982199 | 0.83 | PTGS2 (0.59) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| SCHEMBL7989315 | 0.82 | PTGS2 (0.59) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| SCHEMBL7981972 | 0.81 | PTGS2 (0.51) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| SCHEMBL7984583 | 0.81 | PTGS2 (0.51) | MAPK14PTGS2PTGS1 | |
| SCHEMBL7972882 | 0.81 | PTGS2 (0.47) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| SCHEMBL7985899 | 0.80 | PTGS2 (0.54) | MAPK14PTGS2MAPK13RAF1MAPK9 | |
| Diethylamine SCHEMBL7984563 | 0.79 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |