Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865728 | 0.69 | PARP10 (0.33) | — | |
| SCHEMBL30899498 | 0.69 | PARP10 (0.33) | — | |
| SCHEMBL31649773 | 0.68 | PARP10 (0.33) | — | |
| SCHEMBL31159121 | 0.67 | HTR2C (0.39) | — | |
| SCHEMBL13031034 | 0.62 | HTR2A (0.33) | — | |
| SCHEMBL31159167 | 0.61 | NOTUM (0.47) | — | |
| SCHEMBL31393728 | 0.61 | PARP10 (0.42) | — | |
| SCHEMBL20865736 | 0.60 | ALDH1A1 (0.38) | — | |
| SCHEMBL31702265 | 0.60 | HTT (0.38) | CRBN | |
| SCHEMBL10954874 | 0.56 | GRIN2D (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274594-B1 | ANTICONVULSANTS, ANALGESICS; NERUOPATHIC, CANCER AND DENTAL PAIN; | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-08-14 | — | — | US | disclosed |
| EP-1032570-A1 | ISOQUINOLINE DERIVATIVES AND THEIR THERAPEUTICAL USE | SMITHKLINE BEECHAM PLC (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025709-A1 | ISOQUINOLINE DERIVATIVES AND THEIR THERAPEUTICAL USE | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-05-27 | — | — | WO | disclosed |