Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.46 |
| ▸ | ITGAV | P06756 | 13/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982741 | 0.89 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7355763 | 0.88 | ITGB3 (0.58) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7356042 | 0.87 | ITGB3 (0.54) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7979190 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVITGA2B | |
| SCHEMBL7969225 | 0.86 | ITGB3 (0.51) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7979200 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BSMN1; SMN2 | |
| SCHEMBL7982411 | 0.81 | ITGB3 (0.42) | ITGB3ITGAVITGA2BSMN1; SMN2 | |
| SCHEMBL7982415 | 0.81 | ITGB3 (0.42) | ITGB3ITGAVITGA2BSMN1; SMN2 | |
| SCHEMBL7985900 | 0.81 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL8681923 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | claimed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |