Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.54 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | S100B | P04271 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972038 | 0.97 | PRSS1 (0.59) | TMPRSS2PRSS1LMNASMN1; SMN2TSHR | |
| SCHEMBL7989750 | 0.96 | PRMT1 (0.60) | TMPRSS2PRSS1LMNASMN1; SMN2TSHR | |
| SCHEMBL7987621 | 0.96 | PRMT1 (0.60) | TMPRSS2PRSS1LMNASMN1; SMN2TSHR | |
| SCHEMBL7984022 | 0.96 | PRMT1 (0.60) | TMPRSS2PRSS1LMNASMN1; SMN2TSHR | |
| SCHEMBL7972526 | 0.96 | PRSS1 (0.58) | TMPRSS2PRSS1LMNASMN1; SMN2TSHR | |
| SCHEMBL7982625 | 0.85 | RAB9A (0.55) | PRSS1LMNAHTTF2F10 | |
| SCHEMBL7389439 | 0.83 | RAB9A (0.55) | PRSS1HTTF2F10PLG | |
| SCHEMBL7986856 | 0.82 | HTT (0.57) | LMNASMN1; SMN2HTTF2F10 | |
| SCHEMBL7984063 | 0.82 | RAB9A (0.54) | PRSS1HTTF2F10PLG | |
| SCHEMBL7986111 | 0.82 | RAB9A (0.54) | PRSS1HTTF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | claimed |
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |