Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 18/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979382 | 0.95 | ITGAV (0.71) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982887 | 0.94 | ITGAV (0.64) | ITGAVITGB3ITGA2B | |
| SCHEMBL7980803 | 0.91 | ITGAV (0.57) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982097 | 0.90 | ITGB3 (0.55) | ITGAVITGB3ITGA2B | |
| SCHEMBL7980496 | 0.90 | ITGAV (0.60) | ITGAVITGB3ITGA2B | |
| SCHEMBL7983031 | 0.90 | ITGB3 (0.56) | ITGAVITGB3ITGA2B | |
| SCHEMBL7980493 | 0.89 | ITGAV (0.60) | ITGAVITGB3ITGA2B | |
| SCHEMBL7979146 | 0.88 | ITGB3 (0.53) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982234 | 0.86 | ITGAV (0.67) | ITGAVITGB3ITGA2B | |
| SCHEMBL7982508 | 0.85 | ITGB3 (0.71) | ITGAVITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | claimed |
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | claimed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | claimed |
| US-6214834-B1 | ANGIOGENESIS INHIBITORS; ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | DUPONT PHARMACEUTICALS COMPANY | 2001-04-10 | — | — | US | disclosed |