Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.59 |
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986180 | 0.90 | F2 (0.60) | F2ESR1ESR2ITGA4HRH3 | |
| SCHEMBL7983523 | 0.89 | F2 (0.59) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6595837 | 0.85 | F2 (0.76) | F2ESR1ESR2ITGA4HRH3 | |
| Hydrochloric Acid SCHEMBL7413076 | 0.83 | F2 (0.60) | F2ESR1ESR2ITGA4 | |
| Hydrochloric Acid SCHEMBL6173647 | 0.83 | F2 (0.60) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6605496 | 0.83 | F2 (0.53) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7983864 | 0.82 | F2 (0.52) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7972400 | 0.82 | ESR1 (0.59) | F2ESR1ESR2ITGA4 | |
| SCHEMBL7422725 | 0.81 | F2 (0.58) | F2ESR1ESR2ITGA4 | |
| SCHEMBL6596926 | 0.81 | ITGA4 (0.69) | F2ESR1ESR2ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |