Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219450 | 0.88 | — | — | |
| SCHEMBL29772429 | 0.88 | — | — | |
| SCHEMBL655393 | 0.73 | — | — | |
| SCHEMBL1693960 | 0.65 | HTR2C (0.40) | CHRNB2CHRNA4 | |
| SCHEMBL2042751 | 0.64 | PIK3CG (0.37) | — | |
| Purine SCHEMBL1592255 | 0.64 | KDM4A (0.33) | — | |
| SCHEMBL6032389 | 0.62 | — | — | |
| Benzo[D]Oxazole SCHEMBL28570848 | 0.62 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| Benzo[D]Oxazole SCHEMBL27565510 | 0.62 | CHRNB2 (0.38) | CHRNB2CHRNA4 | |
| SCHEMBL29587733 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575969-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011147753-A1 | ANTIVIRAL ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2011-12-01 | — | — | WO | disclosed |