Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398536 | 0.84 | MEN1 (0.59) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL20906136 | 0.84 | MAPT (0.45) | SMN1; SMN2MAPTNPC1MEN1KMT2A | |
| SCHEMBL2714221 | 0.82 | MRGPRX4 (0.49) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| Methylamine SCHEMBL5152509 | 0.82 | POLB (0.56) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL25619995 | 0.82 | NOTUM (0.42) | SMN1; SMN2MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL12800816 | 0.80 | MAPT (0.51) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL10543265 | 0.80 | S1PR4 (0.56) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL401811 | 0.79 | CSNK2A1 (0.51) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL18077277 | 0.78 | S1PR4 (0.49) | SMN1; SMN2MAPTNPC1RAB9AMEN1 | |
| SCHEMBL14930507 | 0.78 | THRA (0.56) | SMN1; SMN2MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001029014-A1 | ISOTHIAZOLE-5-CARBOXYLIC ESTERS AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-04-26 | — | — | WO | disclosed |