Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986971 | 0.94 | TACR1 (0.51) | TACR1 | |
| SCHEMBL7925920 | 0.90 | TACR1 (0.51) | CCR3TACR1 | |
| SCHEMBL7932611 | 0.84 | CCR3 (0.54) | CCR3TACR1 | |
| SCHEMBL7986452 | 0.84 | TACR1 (0.53) | TACR1 | |
| SCHEMBL7935285 | 0.83 | TACR1 (0.69) | CCR3TACR1 | |
| SCHEMBL7936444 | 0.80 | TACR1 (0.67) | CCR3TACR1 | |
| SCHEMBL7986923 | 0.80 | CCR3 (0.69) | CCR3TACR1 | |
| SCHEMBL7935308 | 0.80 | TACR1 (0.72) | CCR3TACR1 | |
| SCHEMBL7989759 | 0.76 | TACR1 (0.55) | TACR1 | |
| SCHEMBL7926036 | 0.74 | TACR1 (0.55) | CCR3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | claimed |
| US-6191135-B1 | Neurokinin antagonists | BOEHRINGER INGELHEIM KG (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5708006-A | ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5696123-A | ALPHA-PIPERAZINYL BENZYL COMPOUND AS TACHYKININ ANTAGONIST TREATING ASTHMA, BRONCHITIS, SKIN DISORDER, EYE DISEASE, HEADACHE, GASTROINTESTINAL DISORDER | BOEHRINGER INGELHEIM KG (DE) | 1997-12-09 | — | — | US | disclosed |