SCHEMBL7986844

SCHEMBL7986844

O[C@@H]([C@H](O)[C@@H](COCc1cccc(F)c1)OCc1ccccc1)[C@@H](COCc1cccc(F)c1)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAN2A1 Q16706 1/20 0.46
MAN1B1 Q9UKM7 1/20 0.46
CA1 P00915 3/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
IDO1 P14902 2/20 0.44
AGXT P21549 2/20 0.44
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
NR4A2 P43354 2/20 0.41
HCAR2 Q8TDS4 1/20 0.41
AR P10275 1/20 0.41
CHRM3 P20309 2/20 0.39
MAOB P27338 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7975882 1.00 MAN2A1 (0.46) MAN2A1MAN1B1CA1CA2CA7
SCHEMBL7989889 0.87 CA1 (0.47) CA1CA2CA7CA9CHRM3
SCHEMBL7509273 0.87 CA1 (0.47) CA1CA2CA7CA9CHRM3
SCHEMBL7989942 0.87 CA1 (0.47) CA1CA2CA7CA9CHRM3
SCHEMBL7992891 0.87 KDM4E (0.46) MAN2A1MAN1B1IDO1AGXTKDM4E
SCHEMBL5742123 0.87 CA1 (0.56) CA1CA2CA7CA9
SCHEMBL7975427 0.86 CA1 (0.46) CA1CA2CA7CA9
SCHEMBL7990696 0.83 CA1 (0.41) CA1CA2CA7CA9IDO1
SCHEMBL7990573 0.82 CYP4F2 (0.51) CA1CA2CA7CA9KDM4E
SCHEMBL7989604 0.82 CA1 (0.42) CA1CA2CA7CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313177-B1 AS ANTIVIRAL AGENTS PHARMACOR INC. (CA) 2001-11-06 US disclosed