Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989289 | 0.88 | CA1 (0.42) | IDO1MAOB | |
| SCHEMBL7975882 | 0.87 | MAN2A1 (0.46) | KDM4ETDP1IDO1AGXTMAN2A1 | |
| SCHEMBL7986844 | 0.87 | MAN2A1 (0.46) | KDM4ETDP1IDO1AGXTMAN2A1 | |
| SCHEMBL7989311 | 0.87 | CA1 (0.44) | IDO1 | |
| SCHEMBL7987303 | 0.86 | HSP90AA1 (0.43) | KDM4ETDP1IDO1MAOB | |
| SCHEMBL7987648 | 0.86 | HSP90AA1 (0.39) | KDM4ETDP1IDO1LMNAL3MBTL1 | |
| SCHEMBL7447822 | 0.85 | HSP90AA1 (0.44) | KDM4EIDO1L3MBTL1MAOB | |
| SCHEMBL7989824 | 0.83 | ALDH1A1 (0.39) | KDM4EIDO1L3MBTL1MAOBMAPT | |
| SCHEMBL7976011 | 0.83 | CA1 (0.45) | IDO1 | |
| SCHEMBL7986153 | 0.81 | LMNA (0.39) | KDM4ETDP1IDO1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |