Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383858 | 0.97 | KDM4E (0.46) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL4383468 | 0.93 | KDM4E (0.44) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL4378580 | 0.88 | KDM4E (0.43) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL4379129 | 0.87 | FFAR1 (0.39) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL8795425 | 0.85 | FFAR1 (0.39) | PLA2G4BSMN1; SMN2LMNAPLA2G4A | |
| SCHEMBL7990745 | 0.84 | HRH2 (0.57) | L3MBTL1 | |
| SCHEMBL4378557 | 0.83 | POLB (0.42) | KDM4ECYP1A2CYP2D6PDE4ASMN1; SMN2 | |
| SCHEMBL7987723 | 0.83 | HRH2 (0.56) | L3MBTL1 | |
| SCHEMBL4390061 | 0.82 | CYP1A2 (0.40) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL4390064 | 0.82 | CYP1A2 (0.40) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |