Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 5/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990745 | 0.99 | HRH2 (0.57) | HRH2HRH1L3MBTL1THRATHRB | |
| SCHEMBL7987565 | 0.92 | L3MBTL1 (0.55) | HRH2HRH1L3MBTL1THRATHRB | |
| SCHEMBL7994845 | 0.87 | L3MBTL1 (0.48) | HRH2HRH1L3MBTL1 | |
| SCHEMBL7977335 | 0.87 | SMN1; SMN2 (0.51) | HRH2HRH1L3MBTL1 | |
| SCHEMBL7977269 | 0.84 | CES2 (0.45) | L3MBTL1 | |
| SCHEMBL7987718 | 0.83 | PLA2G4B (0.46) | L3MBTL1 | |
| SCHEMBL4376187 | 0.81 | L3MBTL1 (0.59) | HRH2HRH1L3MBTL1 | |
| SCHEMBL7987591 | 0.81 | HRH3 (0.42) | L3MBTL1 | |
| SCHEMBL4381007 | 0.80 | SMN1; SMN2 (0.52) | HRH2HRH1L3MBTL1 | |
| SCHEMBL4383858 | 0.79 | KDM4E (0.46) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |