Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593147 | 0.90 | MEN1 (0.43) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL22441312 | 0.86 | TAAR1 (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL3589541 | 0.86 | TAAR1 (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL21378558 | 0.86 | TAAR1 (0.47) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL9023752 | 0.82 | CYP24A1 (0.41) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL16550740 | 0.82 | MEN1 (0.40) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL15319339 | 0.82 | MEN1 (0.40) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL17372882 | 0.82 | MEN1 (0.40) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL16666612 | 0.82 | MEN1 (0.40) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 | |
| SCHEMBL6935167 | 0.82 | LAP3 (0.44) | TAAR1SLC6A2SIGMAR1MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |