Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925545 | 0.80 | GAA (0.41) | GAA | |
| SCHEMBL14925543 | 0.76 | GAA (0.38) | GAA | |
| SCHEMBL14925537 | 0.72 | GAA (0.38) | GAA | |
| SCHEMBL25718334 | 0.66 | GAA (0.35) | GAA | |
| SCHEMBL798450 | 0.64 | GRM5 (0.31) | GRM5 | |
| SCHEMBL14925526 | 0.64 | CYP3A4 (0.49) | GAAGRM5 | |
| SCHEMBL14925533 | 0.62 | GAA (0.33) | GAA | |
| SCHEMBL19131072 | 0.61 | — | — | |
| SCHEMBL798461 | 0.61 | GRM5 (0.33) | GRM5 | |
| SCHEMBL14925524 | 0.61 | GAA (0.31) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | GAA 1336/4885GRM5 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.